Pan Am Flight 103 explodes over Lockerbie 38 minutes after takeoff on Dec. 21, 1988, killing 259 on board and 11 on ground. Dr. Jim Swire loses daughter Flora and seeks justice with wife Jane.

Following an incident in her past, Cordelia now lives with her twin sister, Caroline in their late father's basement flat.

A modern update finds the famous sleuth and his doctor partner solving crime in 21st century London.